Analytical Chemistry Interview Questions

 
1.
What is deference between the working standard and reference standard?
2.
How do we fix the sample concentaryion in hplc method development. what is the basis?
3.
Suppose we prepared pH buffer solution in lab.and calibrate against NIST solution, and same shall going to used upto 30 days. is it possible to stable pH and apperance? suggest?
4.
What is rs test why we are perfoming rs test?
5.
What is difference between silica used in TLC and HPLC column?
6.
What is use of acetonitrile compare to methanol in RP-HPLC Method development?
7.
How to know HPLC column performance?
8.
What is heavy water?
9.
What is quality controle?
10.
When we get Moisture content by KF higher than by LOD, what does this indicate?
11.
What is Standard deviation?
12.
How to calculate signal to noise ratio by this formula 2H/h where h from where and how to measure?
13.
WHAT IS USE OF ION PAIR REAGENTS?
14.
Explain What is a base line?
15.
IN pH CALIBRATION,CALIBRATION IS DONE FOR pH METER OR ELECTRODE?HOW WILL YOU JUDGE THAT THE METER TO BE CALIBRATED WITH 4,7,9.2 BUFFERS?EXPLAIN TEMPERATURE EFFECTS ON pH?
16.
WILL YOU DRY DST BEFORE FACTOR DETERMINATION BY USING KARL FISHER TITRATOR?
17.
What is deference between the working standard and reference standard?
18.
How do we fix the sample concentaryion in hplc method development. what is the basis?
19.
Suppose we prepared pH buffer solution in lab.and calibrate against NIST solution, and same shall going to used upto 30 days. is it possible to stable pH and apperance? suggest?
20.
What is rs test why we are perfoming rs test?
21.
What is difference between silica used in TLC and HPLC column?
22.
What is use of acetonitrile compare to methanol in RP-HPLC Method development?
23.
How to know HPLC column performance?
24.
What is heavy water?
25.
What is quality controle?
26.
When we get Moisture content by KF higher than by LOD, what does this indicate?
27.
What is Standard deviation?
28.
How to calculate signal to noise ratio by this formula 2H/h where h from where and how to measure?
29.
WHAT IS USE OF ION PAIR REAGENTS?
30.
Explain What is a base line?
31.
IN pH CALIBRATION,CALIBRATION IS DONE FOR pH METER OR ELECTRODE?HOW WILL YOU JUDGE THAT THE METER TO BE CALIBRATED WITH 4,7,9.2 BUFFERS?EXPLAIN TEMPERATURE EFFECTS ON pH?
32.
WILL YOU DRY DST BEFORE FACTOR DETERMINATION BY USING KARL FISHER TITRATOR?