Bio Informatics Interview Questions

 
1.
What is e value?
2.
How is the respiratory system applied to the sport paintball?
3.
How to identify highly mutated aminoacid from clustalw?
4.
Can isolation of DNA done with perfection? how?
5.
What are databases used in bioinformatics?
6.
Explain it is a common experience that if we go on burping simultaneously and consciously(i.e.purposely,as in a non- natural action),our stomach starts aching. Why does this happen?
7.
Which field have wider prospective of job M.sc bioinformatics or M.sc biotechnology?
8.
What are the responsible factors for extinction of flora and fauna?
9.
What is the difference between present and oldest drug discovery methods?
10.
WHY YOU SELECT BIOINFORMATICS AS YOUR MAJOR FIELD?
11.
Derive e-value?
12.
How to run DOCK 6 using cygwin?
13.
What are the main signals used for gene finding in prokaryotic genomes? How are these signals introduced into the search algorithms?
14.
Explain Homology modelling?
15.
What is the meaning of science?
16.
Which of the following sequences contains the pattern [AG]-x
(4)-G-K-[ST] from the PROSITE database?

seq. A: VAGWGKST
seq B: GVLKRGKS
seq. C: AGVLKGRT
seq. D: AGVGKSTP?
17.
What is the main idea of maximum parsimony in phylogenetic tree construction? What are the drawbacks?
18.
What are the main approaches of predicting protein interactions using genomic context analysis?
19.
How you calculate sensitivity and selectivity of Blast?
20.
Suppose you used the NCBI Blast server to look for a match to a fruit-fly gene.

Suppose further that the best alignment contained this
section of an alignment:

Hit from database: XXXXXXXXXXXXXXNFSTSQ

user sequence: SLEAEAAPASISPSNFSSSQ
What do the Xs signify?
21.
What is e value?
22.
How is the respiratory system applied to the sport paintball?
23.
How to identify highly mutated aminoacid from clustalw?
24.
Can isolation of DNA done with perfection? how?
25.
What are databases used in bioinformatics?
26.
Explain it is a common experience that if we go on burping simultaneously and consciously(i.e.purposely,as in a non- natural action),our stomach starts aching. Why does this happen?
27.
Which field have wider prospective of job M.sc bioinformatics or M.sc biotechnology?
28.
What are the responsible factors for extinction of flora and fauna?
29.
What is the difference between present and oldest drug discovery methods?
30.
WHY YOU SELECT BIOINFORMATICS AS YOUR MAJOR FIELD?
31.
Derive e-value?
32.
How to run DOCK 6 using cygwin?
33.
What are the main signals used for gene finding in prokaryotic genomes? How are these signals introduced into the search algorithms?
34.
Explain Homology modelling?
35.
What is the meaning of science?
36.
Which of the following sequences contains the pattern [AG]-x
(4)-G-K-[ST] from the PROSITE database?

seq. A: VAGWGKST
seq B: GVLKRGKS
seq. C: AGVLKGRT
seq. D: AGVGKSTP?
37.
What is the main idea of maximum parsimony in phylogenetic tree construction? What are the drawbacks?
38.
What are the main approaches of predicting protein interactions using genomic context analysis?
39.
How you calculate sensitivity and selectivity of Blast?
40.
Suppose you used the NCBI Blast server to look for a match to a fruit-fly gene.

Suppose further that the best alignment contained this
section of an alignment:

Hit from database: XXXXXXXXXXXXXXNFSTSQ

user sequence: SLEAEAAPASISPSNFSSSQ
What do the Xs signify?